Question

In: Biology

Graft-Versus-Host disease will most likely be a complication of a blood transfusion. T or F Desensitization...

Graft-Versus-Host disease will most likely be a complication of a blood transfusion. T or F
Desensitization to prevent allergies involves the injection of increasing amounts of IgE. T or F
.
Hemolytic disease of the newborn can result from a Rh- mother with a Rh+ fetus. T or F
.
"Immune Privileged" explains how animals tolerate pregnancies without rejecting the fetus. T or F
Which of the following describes a cytotoxic autoimmune reaction?
cells are killed.
immune complexes form.
mediated by T cells.
antibodies react to cell-surface antigens
Symptoms of delayed cell-mediated reactions are due to   
cytokines.
IgE antibodies.
neutrophils.
IgG antibodies.
antigens.

Solutions

Expert Solution

False: Graft-Versus-Host disease will most likely be a complication of a blood transfusion.

It is most likely a complication from organ transplants.

True: Hemolytic disease of the newborn can result from an Rh- mother with a Rh+ fetus.

Immune cells of an Rh- mother are sensitized to Rh factor in a previous pregnancy. involving a Rh+ baby. Once sensitized, in a later pregnancy with Rh+ fetus, immune cells mount an active defense against the Rh factor of the fetus with the help of traversing antibodies. The antigen-antibody reaction in a fetus's blood cause hemolysis.

True: "Immune Privileged" explains how animals tolerate pregnancies without rejecting the fetus.

Immune privilege is a term for sites in the animal body that do not have a strong inflammatory reaction when foreign tissue is encountered. Other than the placenta and fetus several other sites that enjoy immune privilege include: the eye, brain, testicles.

Which of the following describes a cytotoxic autoimmune reaction?

antibodies react to cell-surface antigens

It is a type of autoimmunity where antibodies bind to surface antigens of the cell but do not carry out destruction.

Symptoms of delayed cell-mediated reactions are due to cytokines.

Basically helper T cells recognize the antigens and trigger a chain of stimulative reaction that works slowly to build up excessive cytokines. The cytokines produce effects such as inflammation, tissue death, etc.


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