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In: Chemistry

a. How is iodine-­131 used to identify hyperthyroidism? b. Give two reasons that 201TlCl is a...

a. How is iodine-­131 used to identify hyperthyroidism?

b. Give two reasons that 201TlCl is a popular compound to use for imaging the heart. Explain how this imaging process provides information about the functioning of the heart.

Solutions

Expert Solution

(a) When a small dose of I-131 is swallowed, it is absorbed into the bloodstream in the gastrointestinal (GI) tract and concentrated from the blood by the thyroid gland, where it begins destroying the gland's cells.This is how I-131 is useful for hyperthyrodism.

(b)

Thallous Chloride Tl-201 is the chloride salt form of thallium-201, a cyclotron produced isotope use in diagnostic imaging. Thallous chloride TI-201 accumulates in myocardial cells and other tissues in an analogous way as potassium, and can be evaluated as a function of blood flow. By scintigraphic means, areas with decreased blood flow, consisting of ischemic cells, can be visualized due to decreased uptake of TI-201 in contrast to areas with normal blood flow.

queen_honey_blossom answered 1 year ago
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