Based on what you know about metabolism from the lectures you have had so far in...

Based on what you know about metabolism from the lectures you have had so far in this course, which two of the following would you expect to be the MOST LIKELY to have signs and symptoms that are nearly identical to each other?

		TPID (triose phosphate isomerase deficiency, an inability to make triose phosphate isomerase)
		Arsenate poisoning (arsenate can substitute for phosphate, but bonds between AsO₄^3- and carbohydrates instantly hydrolyze whereas acyl phosphate bonds do not)
		Beriberi, a dietary deficiency of thiamine
		A dietary deficiency of biotin
		Arsenite poisoning (arsenite inactivates lipoamide)

Solutions

Expert Solution

arsenate poisoning and beriberi ( thiamine deficiency) shows similar signs and symptoms

Arsenic interferes with cellular longevity by allosteric inhibition of an essential metabolic enzyme pyruvate dehydrogenase (PDH) complex, which catalyzes the oxidation of pyruvate to acetyl-CoA by NAD+. With the enzyme inhibited, the energy system of the cell is disrupted resulting in cellular apoptosis. Biochemically, arsenic prevents use of thiamine resulting in a clinical picture resembling thiamine deficiency

signs and symptoms : vomiting, abdominal pain , encephalopathy,watery diarrhoea that contains blood .

gladiator answered 1 year ago

Next > < Previous

Related Solutions

What have you learned so far about what determines prices such as the rent for an...

What have you learned so far about what determines prices such as the rent for an apartment? If people cannot afford rent, what are they to do? What are the consequences of controlling rent and for not controlling it? Is the current system fair?

Question 2: Using what you know so far about the dynamics in American families, how are...

Question 2: Using what you know so far about the dynamics in American families, how are they likely to be responding to the global pandemic which has led to social distancing; increased work from home; shuttered schools and day care centers; and higher unemployment?

So far we've learned about a few important cofactors involved with amino acid metabolism. What vitamin...

So far we've learned about a few important cofactors involved with amino acid metabolism. What vitamin is each cofactor also known as? What reactions are each required for? And what are the dietary implications of a deficiency in each cofactor? Pyridoxal Phosphate Tetrahydrofolate Cobalmin

Based on what you know, and the material presented in the course thus far, what are...

Based on what you know, and the material presented in the course thus far, what are the TOP TEN risks associated with starting a new business, and why? Just like in the previous questions, place in order of priority and place a degree of importance/severity on each risk factor. (Hint: some people think the biggest risk is sunk salary you could have earned, or damage to ego, or wasted time, or damaged reputation, or letting down one’s family, or being...

Now that you have had a chance to review the content covered so far, take a...

Now that you have had a chance to review the content covered so far, take a moment to reflect upon what you have learned and post in this discussion board below. Consider one or two of the following statements in your post: Provide a real life situation that pertains to the information in Chapter 4 and 5. Why would knowing whether a linear relation exists be important? Where would this apply? Provide an example. Would it be important to know...

For one important and interesting idea that you have learned so far in the course based,...

For one important and interesting idea that you have learned so far in the course based, write a one page essay beginning with the following statements: Although before this class I believed …….., in fact……..Or, Although it is tempting to believe……., in fact…..Or, Although it might seem that …………… is true, in fact…… Then explain why you or others could believe the idea that is fact incorrect. In other words, what is logical or compelling about this incorrect idea. Then...

Reflect on and relate to what you have learned so far in the course with respect...

Reflect on and relate to what you have learned so far in the course with respect to your ability to calculate gross domestic product and its impact on the economy’s business cycle, unemployment, and inflation; using gross domestic product formulate recommendations for a government’s role in achieving full employment in an economy.

Question