EK is a 53 year old male, who weighs 130 lbs, is given a 350 mg...

EK is a 53 year old male, who weighs 130 lbs, is given a 350 mg loading dose of an anticancer medication. At the same time, a continuous IV infusion is started at a rate of 19 mg/hr. The volume of distribution is 1.4 L/kg and the drug half-life is 7.3 hours. The physician wants drug levels drawn 14 hours after the loading dose was given and the infusion was started. What is the expected plasma drug concentration when the patient's blood sample is collected 14 hours after the infusion began? Note: Assume the infusion is ongoing. Please provide your answer in units of mg/L.\

Solutions

Expert Solution

queen_honey_blossom answered 1 year ago

Next > < Previous

Related Solutions

DD is a 60 year old female, who weighs 102 lbs, is given a 300 mg...

DD is a 60 year old female, who weighs 102 lbs, is given a 300 mg loading dose of an anticancer medication. At the same time, a continuous IV infusion is started at a rate of 13 mg/hr. The volume of distribution is 1 L/kg and the drug half-life is 12.1 hours. The physician wants drug levels drawn 28 hours after the loading dose was given and the infusion was started. What is the expected plasma drug concentration when the...

.The client is a 66 year-old female who weighs 154 lbs and is 5 ft, 4...

.The client is a 66 year-old female who weighs 154 lbs and is 5 ft, 4 in tall. She lives with her retired husband. They own their own home and live with their three dogs. The client watches her 3 year-old granddaughter 2 days per week. She saw her MD today, who admitted her to the hospital for her recent weight gain of 15 lbs, shortness of breath with activity, and ankle edema. Per the patient her symptoms have been...

Joanne is a 39-year-old accountant, who is 5’4” and weighs 165 lbs. She smokes ½ pack...

Joanne is a 39-year-old accountant, who is 5’4” and weighs 165 lbs. She smokes ½ pack of cigarettes per day. At her recent examination, she told her PCP that she has been experiencing heartburn, which has become more frequent and painful. The heartburn occurs after she eats a large meal and is particularly bad after she goes to bed at night. After a series of medical procedures, her PCP diagnosed Joanne with Reflux esophagitis and narrowing of the esophagus. The...

Mr. Andrew Smith is a 50-year-old male, 5 feet 10 inches tall and weighs 265 lbs....

Mr. Andrew Smith is a 50-year-old male, 5 feet 10 inches tall and weighs 265 lbs. He has gained 30 pounds in the past year. He has been diagnosed with heart disease. Testing revealed his total cholesterol is 225 mg/dL, and blood pressure is 150/95. Mr. Smith eats a diet that is high in saturated and Tran’s fats. He also complains of shortness of breath when climbing stairs. Mr. Smith meets with his physician and is started on atorvastatin. Mr....

Mr. Andrew Smith is a 50-year-old male, 5 feet 10 inches tall and weighs 265 lbs....

TR is a 78-year-old female, who weighs 83.2kg (183 lbs. 6oz) and stands 152.4 cm (5...

TR is a 78-year-old female, who weighs 83.2kg (183 lbs. 6oz) and stands 152.4 cm (5 ft.). She states she lives with her spouse of 55 years and both are independent and active. Her code status is DNR and her Physician is Dr. Jon Doe. She states she wears glasses due to an eye injury when she was young and also has hearing aids but left them both of them at home. Allergies: Ace inhibitors—unknown reaction, Actos—dizziness, throat swelling, Endocet—hives,...

Helio is a 48-year-old sedentary male diagnosed with prediabetes who is 250 lbs and 5’7”. Helio’s...

Helio is a 48-year-old sedentary male diagnosed with prediabetes who is 250 lbs and 5’7”. Helio’s VO2max is 26 ml/kg/min. His total daily energy expenditure is 1700 kcal/d and his diet log indicates he eats ~1900 kcal/d (48% CHO, 17% protein, and 35% fat). His doctor prescribes the drug metformin to control his blood glucose and also recommends he see an exercise physiologist and nutritionist to prescribe a lifestyle program to control his weight and prevent the progression to type...

The client is a 53-year-old lawyer who travels internationally.

Patient with Meniere’s Disease: The client is a 53-year-old lawyer who travels internationally. He has noticed progressive sensorineural hearing loss, tinnitus that is interfering with his job performance, and occasional incapacitating vertigo. The health care provider is suspects that the client is suffering from Meniere’s Disease. How would you explain in layman’s terms the pathophysiology of Meniere’s disease to the client: Describe assessment finding that are consistent with the diagnosis of Meniere’s disease: Describe diagnostic finding (Weber and Rinne Test, audiogram,...

A 53-year-old male patient with an established diagnosis of IgG ? multiple myeloma was seen by...

A 53-year-old male patient with an established diagnosis of IgG ? multiple myeloma was seen by a hematologist?oncologist in consultation from an outside hospital. He had previously received 1 cycle of chemotherapy treatment, but he was found to be Intermittently noncompliant with his therapy. The patient reported occasional nosebleeds and fatigue. Except for a slightly cachectic appearance, the physical examination was unremarkable. Laboratory results are shown in Table 1. Serum protein electrophoresis revealed monoclonal paraproteinemia in high abundance marked by...

6. A patient weighs 125.4 lbs. and has an order for Amoxicillin 50 mg/kg/day PO to...

6. A patient weighs 125.4 lbs. and has an order for Amoxicillin 50 mg/kg/day PO to be given in equally divided doses q 8 hr. How many mg will be given per dose? _________mg/dose. How many mL per dose? ______mL/dose. 7. Diltiazem 0.35 mg/kg IV now is ordered for a patient weighing 176 lbs. How many mL will be administered? ______mL 8. Gemcitabine 475 mg IV now is ordered. Following the directions on the medication label, the patient will receive...

Subjects