A male with gigantism (due to paternal duplication of the Igf2 locus on the same chromosome)...

A male with gigantism (due to paternal duplication of the Igf2 locus on the same chromosome) married a normal individual. He worries about having children since they may also have gigantism. What would you tell him?

Question 2 options:

	They will be all healthy.
	Only sons have 50% chance of developing gigantism.

	Children have 50% chance of having gigantism.
	Only daughters have 50% chance of developing gigantism.

Expert Solution

gladiator answered 3 years ago

Chromosome Chromosome Locus Number Locus Number &nb

Chromosome Chromosome Locus Number Locus Number TPOX 2 TH01 11 D3S1358 3 VWA 12 FGA 4 D13S317 13 D5S818 5 D16S539 16 CSF1PO 5 D18S51 18 D7S820 7 D21S11 21 D8S1179 8 Table 1. Locus Alleles Frequency Locus RMP TPOX 8 12 0.535 0.041 TH01 10 10 0.008 D3S1358 16 17 0.222 0.222 FGA 21 23 0.0185 0.134 CSF1PO 11 13 0.301 0.096 D8S51 14 19 0.137 0.038 D21S11 28 29 0.159 0.195 If you haven’t already done so, calculate...

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