True or False ______ Phosphorylation of plasma membrane phospholipids can create binding sites for intracellular signaling...

True or False

______ Phosphorylation of plasma membrane phospholipids can create binding sites for intracellular signaling proteins.

______ RTKs are single pass transmembrane proteins that are inactive until they undergo dimerization.

______ Paracrine signaling refers to signaling over long distances and requires the bloodstream.

______ Nuclear hormone receptor proteins do not directly bind or contact DNA, they utilize a coactivator protein for this purpose.

______ A signal sequence that is formed only when a protein is in its final 3D conformation is

called a signal patch.

______ TCF/LEF1 function as transcriptional activators when bound to Groucho.

Solutions

Expert Solution

2) RTKs are single pass transmembrane proteins that are inactive until they undergo dimerization- True. RTKs undergo dimerization when a ligand (signaling molecule) binds to it.

3) Paracrine signaling refers to signaling over long distances and requires the bloodstream- False.

In paracrine signaling, the signaling molecule released by a cell affects only those target cells which are in close proximity.

In endocrine signaling, bloodstream is required for long distance transmission of signals.

4) Nuclear hormone receptor proteins do not directly bind or contact DNA, they use a coactivator protein for this purpose- True. They bind to a ligand which causes a conformational change in the receptor protein, which in turn binds to a coactivator protein.

5) A signal sequence that is formed only when a protein is in its final 3D conformation is called a signal patch - True.

gladiator answered 1 year ago

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