Question

can you please explain modes of transmission of e.coli

and please please explain virulence factors of E.coli in simple details.

thank you so much

Answer 1

modes of transmission of E coli:

1) consumption of contaminated food

• Raw meat
• Raw milk
• Raw vegetables and sprouts

2) consumption of contaminated water

• If water intended for recreation and human consumption gets contaminated, it results in the spread of E coli

3)animal-human contact

• Playing with animals in zoos
• Inhalation of dust particles

4)person to person contact

• Fecal oral route
• In case of infants and young children
• Due to unhygienic methods

5)intake of contaminated fruits and vegetables

• Contaminated seeds
• Contaminated irrigation water
• Flooding

Virulence factors of E coli-

Virulence factors are the molecules which adds to the effectiveness in the spread of infection by E coli

• E coli species is subdivided into several pathogenic strains causing different intestinal ,urinary tract or internal infection in humans and pathogens
• Virulence factors are as follows:-

1. Adhesins- fimbrial adhesins, afimbrial adhesins, outer membrane proteins
2. Type 3 secretin system
3. Toxins ( oligo peptides and RTX pore forming toxins

All the above molecules directly interact with epithelial cells of intestinal, respiratory and urinary tracts.

Hope the answer is clear to you...