In: Biology
Which of the following is true about interferon?
It is released by uninfected cells during a viral infection
It is produced by virally infected cells during a viral infection, whereupon it inhibits further viral replication within the cells where it is made.
It is produced by virally infected cells to activate helper T-cells.
It is released by virally infected cells to induce an antiviral state in uninfected cells. It is released by cells in lymph nodes to attract T cells to the lymph node.
Interferons
Interferons belong to class of proteins called Cytokines. They are a part of the defence system of the body . Major signalling proteins help in communication between cells.
In the question there are 5 statements regarding interferons. We want to select the correct one ,
* It is released by uninfected cells during a viral infection.
The statement is incorrect. Interferons are released by virus infected cells in the body.
* It is produced by virally infected cells during a viral infection , whereupon it inhibits further viral replication within cells where it is made.
The statement is incorrect. Interferon doesnot directly inhibit virus replication instead it actas a signal to nearby cells. And stimulates nearby cells to produce proteins against virus replication.
* It is produced by virally infected cells to activate helper T cells.
The statement is incorrect. Interferon is not directly involved in activation of helper T cells.
* It is released by virally infected cells to induce an antiviral state in uninfected cells.
The statement is True. Interferon is released as a messenger by virally infected cells to induce an antiviral state in nearby uninfected cells. This prevents further viral infection.
* It is released by lymph nodes to attract T cells to the lymph node.
The statement is incorrect. Interferons are not released by lymph nodes, they are released by virally infected cells.
Fourth statement is True.
IT IS RELEASED BY VIRALLY INFECTED CELLS TO INDUCE AN ANTIVIRAL STATE IN UNINFECTED CELLS is the true statement.