Question

Vitamins serve as co-enzymes in many biochemical reactions. What vitamins (co-enzymes) would you supply bacteria and which you would remove from the medium to prevent accumulation of fat by bacteria.

Answer 1

Answer :

Thiamin or vitamin B1 is a water soluble vitamin, helps in fat metabolism or usage.

Vitamin pyridoxal -B6, is more involved in aminoacid and protein metabolism. But recent studies show restriction of B6 impair fattyacid synthesis.

B12 is a cofactor for regulating long chain fatty acyl CoA transfer to mitochondria leading to fattyacid accumulation in cytosol.

Niacinamide, pantothenic acid and riboflavin - B2, converted to coenzymes help in fattyacid synthesis.

biotin, folic acid.is involved in fattyacid synthesis.

Vitamin C D, increases fattyacid oxidation.

Fat soluble A E helps in fattyacid synthesis.

Vitamin E inhibit fattyacid oxidation.

Though these are role of different coenzymes, the prime coenzymes favouring fat synthesis are Niacinamide, pantothenic acid, riboflavin. So these 3 vitamins should be removed from the medium.

The main coenzymes which oxidize or remove fattyacid are thiamine-B1, vitamin C and vitamin D. So these 3 should be added to the medium.