Question

In: Biology

10. Which of the following would be the most detrimental mutation? A. AGCTCTGAT -> ACCTCTGAT B....

10. Which of the following would be the most detrimental mutation?

A. AGCTCTGAT -> ACCTCTGAT

B. AGCTCTGAT -> AGCTCTGATGAT

C. AGCTCTGAT -> ACCTCTGAA

D. AGCTCTGAT -> AGCTCGAT

Solutions

Expert Solution

Answer =

10. Which of the following would be the most detrimental mutation?

Detrimental mutation that is harmful mutation is the addition or deletion mutation which results in a frame shift.they lead to non functional protein.

B. AGCTCTGAT -> AGCTCTGATGAT

here is addition of three bases. GAT bases are added.

is more deterimental because three bases are added, which leads to non functional protein.

INCORRECT OPTIONS :

A. AGCTCTGAT -> ACCTCTGAT

here is second G is replaced by C.it is substitution mutation.

least harmfull.

C. AGCTCTGAT -> ACCTCTGAA

here is second G is replaced by C and last T is replaced by A.It is substitution type of mutation.

here is no addition or deletion of bases.therefore is least deterimental.

D. AGCTCTGAT -> AGCTCGAT

here is deletion of sixth Thymine.here is only one base is deleted thefore is a type of frameshift mutation but less detrimental than option B.


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