In: Biology
10. Which of the following would be the most detrimental mutation?
A. AGCTCTGAT -> ACCTCTGAT
B. AGCTCTGAT -> AGCTCTGATGAT
C. AGCTCTGAT -> ACCTCTGAA
D. AGCTCTGAT -> AGCTCGAT
Answer =
10. Which of the following would be the most detrimental mutation?
Detrimental mutation that is harmful mutation is the addition or deletion mutation which results in a frame shift.they lead to non functional protein.
B. AGCTCTGAT -> AGCTCTGATGAT
here is addition of three bases. GAT bases are added.
is more deterimental because three bases are added, which leads to non functional protein.
INCORRECT OPTIONS :
A. AGCTCTGAT -> ACCTCTGAT
here is second G is replaced by C.it is substitution mutation.
least harmfull.
C. AGCTCTGAT -> ACCTCTGAA
here is second G is replaced by C and last T is replaced by A.It is substitution type of mutation.
here is no addition or deletion of bases.therefore is least deterimental.
D. AGCTCTGAT -> AGCTCGAT
here is deletion of sixth Thymine.here is only one base is deleted thefore is a type of frameshift mutation but less detrimental than option B.