Describe how methylation occurs on newly replicated DNA

Expert Solution

Answer.) DNA methylation in bacteria is regularly thought of in its part to shield DNA from limitation endonucleases. Notwithstanding this part, be that as it may, thinks about in Escherichia coli, Salmonella enterica serovar Typhimurium (alluded to as S. enterica from this point forward) and Caulobacter crescentus have demonstrated that methylated bases have other biological capacities. In these cases, the methylated bases are not some portion of a limitation/adjustment framework and the chemicals that create them are frequently alluded to as orphan or singular DNA methyltransferases. The postreplicative DNA methylation created by these catalysts superimposes on the essential DNA sequence optional data that has hugeness for DNA exchanges, for example, translation, transposition, start of chromosome replication, mRNA usage and counteractive action of transformations by DNA repair. These alterations are realized in two ways, the first being essentially an adjustment in the consistent state level of the methyltransferase either up or down from ordinary. The second mechanism is through the setup of the nucleotide sequence subject to methylation; it can exist as symmetrically methylated, unmethylated or two conceivable hemi-methylated courses of action.

gladiator answered 1 year ago

What is the relationships between DNA methylation & Epigenetics and DNA methylation & Imprinting?

Describe the way in which DNA is replicated with reference to the following: (a) The formation...

Describe the way in which DNA is replicated with reference to the following: (a) The formation of a replication bubble with 2 replication forks in opposite directions,the involvement of Okazaki fragments in replication, the synthesis of leading and lagging strand and the direction in which chain elongation occurs.

Describe the role of DNA methylation in eukaryotic gene expression.In your answer explain how patterns of...

Describe the role of DNA methylation in eukaryotic gene expression.In your answer explain how patterns of methylation are maintained after DNA replication. (include diagram)

In a linear fragment of DNA, the ends can not be replicated by DNA polymerases.

What are the SD sequences? Found in the promoters of RNA polymerase I Found in the promoters of RNA polymerase II Found in the promoters of RNA polymerase III Ribosome binding sites in prokaryotic mRNA Ribosome binding sites in eukaryotic mRNA In a linear fragment of DNA, the ends can not be replicated by DNA polymerases. Eukaryotes use telomerase enzyme to replicate chromosome tips. This enzyme has DNA polymerase activity RNA polymerase activity Reverse transcriptase activity DNA ligase...

Discuss how aging in mice is reflected in the methylation status of DNA

i) Describe the role of DNA methylation in eukaryotic gene expression.Within your answer explain how patterns...

i) Describe the role of DNA methylation in eukaryotic gene expression.Within your answer explain how patterns of methylation are maintained after DNA replication. ii) With reference to single gene in mice, describe how diet can impact on DNA methylation and consequently the expression of that gene

Describe, in detail, how synthesis of a lagging strand of DNA occurs and WHY it is...

Describe, in detail, how synthesis of a lagging strand of DNA occurs and WHY it is discontinuous. Be as descriptive as possible.

What does “semi-discontinuous” DNA replication mean? Explain in words how the lagging DNA strand is replicated...

What does “semi-discontinuous” DNA replication mean? Explain in words how the lagging DNA strand is replicated in bacteria. What specific enzymatic activities does DNA polymerase I have? Name each activity and explain its role in DNA replication. If DNA polymerase I lacked its 3’-5’ exonuclease activity, what specific consequences with respect to DNA replication would be observed? What consequences would be observed if, instead of DNA pol I, DNA polymerase III lacked its 3’-5’ exonuclease activity? Explain your answers.

DNA is replicated by the semi-conservative model. Describe this process in eukaryotes (linear chromosomes). Include what...

DNA is replicated by the semi-conservative model. Describe this process in eukaryotes (linear chromosomes). Include what enzymes are involved and what is their role in the process? What happens at the ends of linear chromosomes?

If a segment of DNA were replicated without any errors, the replicated strand would have the following sequence of nucleotides:

Base substitution mutations and frameshift mutations If a segment of DNA were replicated without any errors, the replicated strand would have the following sequence of nucleotides:5' - ACTACGTGA - 3'Sort the following replicated DNA sequences by the type of point mutation each contains (frameshift, base substitution, or neither), as compared to the correct sequence shown above. Sort the items into the appropriate name as frameshift mutation, base substitution mutation and or neither5'-ACTCGTGA-3'5'-ATTACGTGA-3'5'-ACTACGTGT-3'5'-ACTAAGTGA-3'

Question