In: Biology
Question 20
An example of a suppressor mutation would be
A mutation that suppresses cell growth |
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An intergenic mutation that increases the activity of a protein performing a different function as the mutated protein |
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An intragenic mutation that restores the inactive protein's structure |
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An intergenic mutation that activates a transcription factor that increases the expression of a normal protein |
Question 23
The mechanism for reactive oxygen species to cause mutation is
the reactive oxygen species stabilize different tautomeric forms of the bases causing inappropriate pairing |
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thymine bases are dimerized which causes a break in the DNA which is not repaired correctly |
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guanine is depurinated by the reactive oxygen species and if it is not repaired can result in any base being inserted |
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bases are oxidized to a variety of different products which might pair with a different base than the original base would have |
Answer 20. A mutation is a change in nucleotides sequence in the DNA that can occur during replication and affect the protein function. There are different types of mutations
Suppressor mutation is a mutation that occurs in genes and suppresses the earlier existing mutation in the cell and restores the phenotype of a cell. Suppressor mutation can occur within the same gene having original mutation (intragenic) or can occur in some other place in the genome apart from the gene having an original mutation (intergenic). Therefore, an example of suppressor mutation would be an intragenic mutation that restores the inactive protein structure is the right answer.
A mutation that suppresses cell growth is not the right answer as suppressor mutation is compensatory in nature and compensate for the earlier existing mutation and revert the phenotype. An intergenic mutation that increases the activity of a protein performing a different function as a mutated protein is not the right answer as mutation takes place in different genes and provide the suitable alternatives to proteins to restore the prior existing phenotype. An intergenic mutation that activates a transcription factor that increases the expression of the normal protein is not the right answer as suppressor mutations do not increase or decrease the protein activity and their main is to restore the phenotype of a protein/cell which was present before the original mutation.