In: Biology
-Draw/write out the cycle of ATP hydrolysis. Does this look familiar? What other proteins use ATP for their activity?
-Comment on the efficiency of motor proteins compared to that of a car.
ATP is hydrolyzed into ADP in the following reaction:
ATP+H2O→ADP+Pi+free energy.
the hydrolysis of ATP to ADP is reversible. The reverse reaction combines ADP + Pi to regenerate ATP from ADP. Since ATP hydrolysis releases energy, ATP synthesis must require an input of free energy. ADP is combined with a phosphate to form ATP in the following reaction:
ADP+Pi+free energy→ATP+H2O
This ATP hydrolysis cycle is used for muscle contraction, the establishment of electrochemical gradients across membranes, and biosynthetic processes necessary to maintain life. All these processes involve many different proteins and reactions. Mostly the reactions are endothermic and they require energy in the form of ATP to power their reactions.
Motor proteins are molecular motors that use ATP hydrolysis to move along cytoskeletal filaments within the cell. This can work at near 100% efficiency whereas car engines have a maximum efficiency of about 40 tp 50%.