In: Chemistry
13. The following calibration data were obtained for a total organic carbon analyzer (TOC) measuring TOC in water:
| 
 Concentration, ug/l  | 
 Number of replicates  | 
 Mean Signal  | 
 Standard Deviation  | 
| 
 0  | 
 20  | 
 0.03  | 
 0.008  | 
| 
 6.0  | 
 10  | 
 0.45  | 
 0.0084  | 
| 
 10.0  | 
 7  | 
 0.71  | 
 0.0072  | 
| 
 19.0  | 
 5  | 
 1.28  | 
 0.015  | 
Calculate the calibration sensitivity.
What is the detection limit for this method?
Calculate the relative standard deviation for each of the replicate sets.
Step I
Plot the concentration vs mean signal to get the slope which will be the calibration sensitivity of the TOC analyser.

m = 0.0656
Step II
Detection limit = (k*Sb)/m
Step III
Just put values of Standard deviation and m with k = 2 or 3 based on % of confident interval and calculate the limit of detection.