What is the number of ATP and ATP equivalents that can be produced via oxidative phosphorylation...

What is the number of ATP and ATP equivalents that can be produced via oxidative phosphorylation per cycle of the Citric Acid Cycle (CAC), starting from pyruvate? B) What is the number of ATP and ATP equivalents that can potentially be produced if Complex I of the Electron Transport System (ETS) is inhibited? C) If Complex II of the ETS is inhibited? D) If Complex III of the ETS is inhibited? E) If Complex IV of the ETS is inhibited?

Solutions

Expert Solution

What is the number of ATP and ATP equivalents that can be produced via oxidative phosphorylation per cycle of the Citric Acid Cycle (CAC), starting from pyruvate?

link reaction produces 1 NADH2

and in citric acid cycle 3 NADH2 + 1 FADH2 + 1 ATP

so total ATP produced = 1

ATP equivalents are NADH2 = 4 and FADH2= 1

B) What is the number of ATP and ATP equivalents that can potentially be produced if Complex I of the Electron Transport System (ETS) is inhibited?

None of the NADH2 will produce ATP, due to inhibition of complex I.

but FADH2 will go through this complex producing 1.5 ATP in Glycolate-glyoxylate shuttle.

So Total ATP from citric acid cycle = 1+1.5 = 2.5 ATP equivalent

C) If Complex II of the ETS is inhibited?

the NADH2 will produce 2.5 ATP per molecule.

so 4 NADH2 will produce 10 ATP

D) If Complex III of the ETS is inhibited

If Complex III of the ETS is inhibited?

Only 1 ATP will be produced

E) If Complex IV of the ETS is inhibited?

only 1 ATP produced from the citric acid cycle, the organism will die due to the absence of terminal electron acceptor.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Can organisms use both mechanisms of ATP? (Oxidative Phosphorylation and substrate-level phosphorylation)

What is substrate-level phosphorylation ? What is oxidative phosphorylation ? Explain how cellular respiration produces ATP...

What is substrate-level phosphorylation ? What is oxidative phosphorylation ? Explain how cellular respiration produces ATP from molecules with high potential energy, such as glucose ? Describe the four components of cellular respiration? What goes into each and comes out of each? ? What is fermentation? How are cellular respiration and fermentation regulated? ? Describe how fermentation operates in the absence of the electron transport chain? ? What does cellular respiration do? What is the chemical equation? ? What is...

For ATP synthesis by oxidative phosphorylation, the P/O ratios of NADH and FADH2 are ~2.5 and...

For ATP synthesis by oxidative phosphorylation, the P/O ratios of NADH and FADH2 are ~2.5 and ~1.5, respectively. Explain how mitochondrial electron transport, ATP synthase, and other membrane processes account for these numbers?

The ATP that is generated in glycolysis is produced by substrate-level phosphorylation

ATP synthesis in glycolysis substrate-level phosphorylation The ATP that is generated in glycolysis is produced by substrate-level phosphorylation, a very different mechanism than the one used to produce ATP during oxidative phosphorylation. Phosphorylation reactions involve the addition of a phosphate group to another molecule. Sort the statements into the appropriate bin depending on whether or not they correctly describe some aspect of substrate-level phosphorylation in glycolysis.

What is the production of ATP both directly and through electron transport/oxidative phosphorylation when: (i) one...

What is the production of ATP both directly and through electron transport/oxidative phosphorylation when: (i) one mole of glucose is converted to two moles of acetyl CoA. (ii) one mole of acetyl CoA is metabolised to CO2 and H2O via the citric acid cycle. (iii) one mole of glucose is completely metabolised to CO2 and H2O via glycolysis, the pyruvate dehydrogenase reaction and the citric acid cycle. How do you calculate this?

In comparing oxidative and substrate-level phosphorylation, which of the following is unique to oxidative phosphorylation? A....

In comparing oxidative and substrate-level phosphorylation, which of the following is unique to oxidative phosphorylation? A. ATP synthesis fueled by a proton motive force generated as a result of the movement of electrons down an electron transport chain. B. ATP synthesis that occurs as a result of coupling the exergonic breakdown of a high-energy organic molecule to phosphorylation C. glucose oxidation D. NADH production

where is the energy used to make ATP during oxidative phosphorylation in the mitochondria originate from?

The oxidative phosphorylation system for ATP synthesis consists of many large protein complexes and their functions...

The oxidative phosphorylation system for ATP synthesis consists of many large protein complexes and their functions are described below in a box. Which is incorrect? Select one: a. Only Complex I, III, IV are H+ pumps. b. CoQ and CytC are the electron carriers between the complexes. c. Fo-F1-ATPase is where ATP is synthesized. d. Complex III has the Q cycle. e. None of these

Oxidative phosphorylation = ETC + chemiosmosis -where does it take place, reactants, products, amount of ATP...

Oxidative phosphorylation = ETC + chemiosmosis -where does it take place, reactants, products, amount of ATP produced, chemisosmosis, proton motive force, ATP synthase

ATP formed during the Krebs cycle is considered _________________ phosphorylation. Substrate level Oxidative Photo Simple

Subjects