Question

When the energetic change of a reaction is high or low, what type of pathway will glucose take and what matabolic needs of a muscle or liver cell.

Answer 1

In contracting skeletal muscle (energetic) overwhelming activity, the rate at which glycolysis produces pyruvate surpasses the rate at which the citric acid cycle oxidizes it. Under these conditions, also, the rate of formation of NADH by glycolysis is more prominent than the rate of its oxidation by oxygen consuming digestion. Proceeded with glycolysis relies upon the accessibility of NAD+ for the oxidation of glyceraldehyde 3-phosphate. The accumulation of both NADH and pyruvate is turned around by lactate dehydrogenase, which oxidizes NADH to NAD+ as it reduces pyruvate to lactate. lactate is a deadlock in metabolism. It must be changed over once again into pyruvate before it can be used. The main reason for the diminishment of pyruvate to lactate is to recover NAD+ so glycolysis can continue in dynamic skeletal muscle and erythrocytes. The formation of lactate buys time and shifts some metabolic burden from muscle to different organs. Pyruvate in the liver is changed over into glucose by the gluconeogenic pathway. Glucose at that point enters the blood and is taken up by skeletal muscle. Consequently, the liver glucose to contracting skeletal muscle, which gets ATP from the glycolytic transformation of glucose into lactate. Contracting skeletal muscle supplies lactate to the liver, which utilizes it to combine glucose.