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phamacology 1 homework: Giving examples, explain how the bioavailability of drugs would be affected by these...

phamacology 1 homework:

Giving examples, explain how the bioavailability of drugs would be affected by these administration routes: oral ,sublingual, and rectal administration routes

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Expert Solution

BIOAVAILABILITY:- The fraction of drug which reaches the circulation after undergoing 1st pass metabolism (some amount of drug is metabolised by the liver before relaying it to the circulation) in the liver.

Oral administration:- Bioavailability 60-70%

Sublingual :- Bioavailability 100%

Rectal. :- Bioavailability 30-40%

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