A mutation replaces the original amino acid, leucine, with threonine in a large protein. The altered...

A mutation replaces the original amino acid, leucine, with threonine in a large protein. The altered protein still functions, but less efficiently. What amino acid might replace leucine but with less effect on protein functions? What amino acid might replace leucine but with even a worse effect on the how the protein functions?

a) less effect if lysine; worse if alanine

b) less effect if methionine; worse if lysine

c) less effect if methionine; worse if alanine

d) less effect if glutamate; worse if lysine

e) less effect if lysine; worse if methionine

Solutions

Expert Solution

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Turkey (protein) has many essential amino acids such as tryptophan, threonine, isoleucine, lysine and phenylalanine. Threonine...

Turkey (protein) has many essential amino acids such as tryptophan, threonine, isoleucine, lysine and phenylalanine. Threonine is a large amino acid and will broken be down into two products: pyruvate and succinyl CoA which are then fed into the citric acid cycle and electron transport chain. Phenylalalanine is broken down into acetyl CoA and fumarate and fed into the citric acid cycle and electron transport chain. Mayonnaise (fatty acid) has omega 3 alpha linolenic acid (18:3Δ9,12,15) and omega 6 linoleic...

Please give reason/reasons why the amino acid threonine is hydrophobic and state why threonine is more...

Please give reason/reasons why the amino acid threonine is hydrophobic and state why threonine is more hydrophobic than aspartic acid. Use the chemistry of the amino acids to support your argument

Which amino acid is the most hydrophobic? (1pt) Arginine Aspartic Acid Leucine Serine Tyrosine

The amino acid leucine has two titratable groups, the α-amino, pKa 9.6 and the α-carboxyl, pKa...

The amino acid leucine has two titratable groups, the α-amino, pKa 9.6 and the α-carboxyl, pKa 2.4. Calculate the ratio of acidic and basic forms and express them as [A]/[HA] ratio or [B]/[BH] of the titrating group at the following pH values: α-carboxyl @ 1.4, 1.9, 2.4, 2.9, 3.4; α-amino @ 8.1, 8.6, 9.1, 9.6, 10.1. Plot pH vs. [B]/[BH] for each group, on the same graph. Compare similarities or disparities in the titration of each group.

What do you think your 93rd amino acid is for this protein? the amino acid sequence...

What do you think your 93rd amino acid is for this protein? the amino acid sequence of the protein coded for by the wild-type TYRP1 is just below.

“Protein A” is phosphorylated at one amino acid by a kinase, “protein B”, and dephosphorylated by...

“Protein A” is phosphorylated at one amino acid by a kinase, “protein B”, and dephosphorylated by a phosphatase, “protein C”. You have purified all three of these proteins and want to determine the structural changes that occur when protein A is phosphorylated or dephosphorylated. Explain in detail how you would go about designing and conducting this investigation.

“Protein A” is phosphorylated at one amino acid by a kinase, “protein B”, and dephosphorylated by...

“Protein A” is phosphorylated at one amino acid by a kinase, “protein B”, and dephosphorylated by a phosphatase, “protein C” You want to determine the mechanisms of protein B and C. What experimental information would you need in order to propose a reasonable mechanism? Explain.

A heptapeptide is shown to have the amino acid composition: phenylalanine glutamate methionine valine lysine threonine...

A heptapeptide is shown to have the amino acid composition: phenylalanine glutamate methionine valine lysine threonine and histidine. I treatment of the heptapeptide with cyanogen bromide yields a tetra and a tri-peptide II treatment of the tetrapeptide with dansyl chloride yields the dansyl derivative of histidine upon acid hydrolysis III treatment of the tetrapeptide with trypsin yields 2 dipeptides IV treatment of the tripeptide with carboxy peptidase yields primarily valine V a single round of Edman degradation of the tripeptide...

(b) After the newly formed protein leaves the ribosome the first amino acid in the protein,...

(b) After the newly formed protein leaves the ribosome the first amino acid in the protein, methionine, is removed. What specific type of enzyme catalyzes this reaction? (c) When benzo[a]pyrene is formed in the burning of meat. What substance(s) in the meat is the source of the aromatic rings in the product? (d) How do drug manufacturers make most drugs water soluble? (e) What is the name of the reaction that would convert a RNA nucleoside into a DNA nucleoside?

19.A mutation that changes an amino acid-coding codon to a stop codon is classified as: A...

19.A mutation that changes an amino acid-coding codon to a stop codon is classified as: A – Silent B – Missense C – Nonsense D – Neutral 20.Spontaneous mutations can arise from: A – All answers are correct B – A base gets damaged C – DNA polymerase inserts an incorrect nucleotide D – A loop occurs during replication 21.DNA Repair Systems: A – Counteract spontaneous and induced mutations B – Counteract induced mutations only C – Counteract amino acid...

Subjects