Question

A mutation replaces the original amino acid, leucine, with threonine in a large protein. The altered protein still functions, but less efficiently. What amino acid might replace leucine but with less effect on protein functions? What amino acid might replace leucine but with even a worse effect on the how the protein functions?

a) less effect if lysine; worse if alanine

b) less effect if methionine; worse if lysine

c) less effect if methionine; worse if alanine

d) less effect if glutamate; worse if lysine

e) less effect if lysine; worse if methionine

Answer 1