Which compliment pathway involves binding of a soluble pattern recognition receptor to mannose on the surface...

Which compliment pathway involves binding of a soluble pattern recognition receptor to mannose on the surface of the pathogen?

A) Alternative Pathway

B) Classic Pathway

C) Mannose-binding Lectin Pathway

Expert Solution

Answer :- C i.e Mannose-binding Lectin Pathway.

Explanation :- It is a complement pathway where lectins act as a soluble pattern recognition receptors that recognise and bind to specific carbohydrate target. This pathway is activated by terminal mannose residues of glycoprotein or polysaccharides found on the surface of bacteria. This pathway doesn't depend upon other factor for activation like antibody. It is activated by binding of mannose binding lectin to mannose residues. These terminal mannose residues are not found on the surface of mammalian cells , and so the lectin pathway of complement activation may be responsible for discrimination between self and non self . Because this pathway is activated in the absence of antibody , and is also the part of innate immune defence.

So from the above discussion we can conclude that the answer is option "C" i.e Mannose-binding Lectin pathway.

gladiator answered 1 year ago

Which compliment pathway(s) results in the production of MAC? Which compliment pathway(s) involves antibodies despite being...

Which compliment pathway(s) results in the production of MAC? Which compliment pathway(s) involves antibodies despite being part of the innate immune system? (multiple answers from the choices below are allowed, if applicable) A). Manose-binding Lectin Pathway B). Classic Pathway C). Alternative Pathway

1. All signaling begins with the binding a soluble ligand to a receptor on the exterior...

1. All signaling begins with the binding a soluble ligand to a receptor on the exterior cell surface. True or False 2. Signaling occurs in the absence of any use of energy. True or False. 3. Name one cellular response controlled by a signaling cascade initiated by an extracellular signaling molecule.

trace the steps of a long and indirect signaling pathway from a cell-surface receptor to a...

trace the steps of a long and indirect signaling pathway from a cell-surface receptor to a change in gene expression in the nucleus . compare this pathway with an example of a short and direct pathway from cell-surface to the nucleus.

The G protein coupled receptor pathway involves the activation of many different proteins or synthesis of...

The G protein coupled receptor pathway involves the activation of many different proteins or synthesis of molecules. For the following pairs of proteins/molecules describe which of the pair is activated/synthesized by the other and how this occurs. a. protein kinase A and cAMP b. adenylyl cyclase and cAMP c. G protein coupled receptor and G protein d. protein kinase A and another protein kinase

Receptor binding motifs such as RGD have highly selective recognition for cell adhesion. Outline a strategy...

Receptor binding motifs such as RGD have highly selective recognition for cell adhesion. Outline a strategy for incorporating a cell adhesion. Outline a strategy for incorporating a cell adhesion recognition domain to a biomaterial. Address the problems surrounding domain quantity, type and affinity in your discussion.

Explain the cell signaling pathway which involves membrane receptor (tyrosine kinase receptors and G protein-coupled receptors)....

Explain the cell signaling pathway which involves membrane receptor (tyrosine kinase receptors and G protein-coupled receptors). Use ONE (1) specific example to explain each reception pathway. The details of the summary should be concise and informative. The length of the summary for each type of membrane receptor should be less than 200 words.

Which of the following consequences of a signaling molecule binding to its receptor is NOT a...

Which of the following consequences of a signaling molecule binding to its receptor is NOT a short-term response? chromatin remodeling, resulting in transcriptional changes ubiquitination of a target protein, resulting in its degradation phosphorylation by a kinase cAMP binding and protein activation

2. Describe the subcellular scheme by which a transmembrane cell surface receptor protein such as the...

2. Describe the subcellular scheme by which a transmembrane cell surface receptor protein such as the platelet derived growth factor receptor gets synthesized and placed at the cell surface. Start with a gene (DNA) but focus primarily on cellular endomembrane systems.

Question