Question

Mark the following as True/False

The nuclease Cas9 is encoded by the human genome

Proto-oncogenes are more commonly found in individuals with cancer than in those without cancer

The bacterial genome contains viral RNA that protects it from future viral infections

Embryonic stem cells express high levels of the “Yamanaka factors”.

Beta-amyloid plaques in neurons are associated with Alzheimer’s Disease.

Answer 1

Ans. The nuclease Cas9 is encoded by the human genome - False ( Cas9 is encoded by bacterial genome for defense mechanism that protect bacteria from viruses).

Proto- oncogenes are more commonly found in individuals with cancer than in those without cancer - False ( proto- oncogenes cannot cause cancer unless a mutations occurs in the gene that turn it into an oncogene. Individuals without cancer, proto- oncogenes plays role in apoptosis and also provide signal for cell division).

Bacterial genome contains viral RNA that protect it from future viral infections - True. ( CRISPR RNA of bacteria is complementary with viral RNA so that after hybridization between both of them, Cas9 cut this viral RNA into pieces).

Embryonic stem cells express high levels of the " Yamanaka factors" - True. ( Yamanaka factors like Oct3/4, Sox2, klf4 etc. are highly expressed in embryonic stem cells).

Beta- amyloid plaques in neurons are associated with Alzheimer's disease - True. ( Beta- amyloid plaques are toxic. In Alzheimer's individual, this plaques are collect between neurons and disrupts their function).