Question

UAUAGC is the genome of a virus. What is the resulting mRNA and what intermediates nucleotide sequences are needed (if any) to produce the mRNA if the above virus is a: a. influenza virus? b. coronavirus? c. T4 phage?

Answer 1

a. Influenza virus have negative strand RNA virus which after entering into host form its complementary strand by virus coded RNA dependent RNA polymerase. Then the Double stranded RNA is transcribed into mRNA. mRNA sequence will be complementary to negative strand RNA and will be identical to newly synthesized positive strand RNA. So

Intermediate double stranded genomic RNA sequence : UAUAGC / AUAUCG

mRNA sequence will be AUAUCG

b. Corona virus have positive strand RNA which means the mRNA produced will have identical sequence with the RNA genome present in the coronavirus. After entering into host the positive stranded RNA form complementary negative sense strand by the enzyme RNA dependent RNA Polymerase.. Then this duplex RNA (intermediate form) form mRNA which is identical to the positive strand initially present in the coronavirus .

Intermediate double stranded genomic RNA sequence : UAUAGC / AUAUCG

mRNA sequence will be UAUAGC

c. T4 phage is a DNA virus. So, RNA cannot be its genome.