Genome Type: Single-stranded DNA Are host proteins needed for replication of the genome? Are any virus-specific...

Genome Type: Single-stranded DNA

Are host proteins needed for replication of the genome?

Are any virus-specific proteins used for replication of the genome? (Provide names)

Are any viral proteins needed from replication brought into the cell with the genome?

Solutions

Expert Solution

For the single-stranded DNA virus, replication of the viral genome is dependent on the host DNA polymerase.

It is been believed that non-structural protein 1 or NS1 acts as an origin recognition protein of the produced double-stranded DNA and helps in viral DNA formation.

No, viral protein is brought into the host cell by the viral genome.

Single-stranded DNA viruses are not well studied. It is been known that after infection, these viral genomes go inside the nucleus where they must form a dsDNA which is required for the expression of the viral proteins. At this time, the host DNA polymerase is used for the replication and the 3' end of the ssDNA folds back and serves as a primer for the new strand synthesis.

gladiator answered 1 year ago

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