Question

In: Biology

1.The RB alleles are defined as: RB = Wildtype and rb = loss of function. A...

1.The RB alleles are defined as: RB = Wildtype and rb = loss of function.

A retinal cell with the genotype RB/rb will display the retinoblastoma phenotype.

True

False

2.Retinal cells with the genotype RB/RB will show _______________ growth, while retinal cells with the genotype rb/rb will show _______________ growth.

group answers

a.controlled; controlled

b.uncontrolled; controlled

c.controlled; uncontrolled

d.uncontrolled; uncontrolled

3.What will happen to a cell with oncogenic Ras?

Group of answer choices

a.The cell cycle will slow down, and it will take longer for the cell to divide.

b.It will progress through the cell cycle normally.

c.It will stop the cell cycle and undergo senescence.

d.It will experience uncontrolled growth

4.True or False. You have extracted DNA from an organism. Next-Gen sequencing is technique that will allow you to determine the sequences of all the genes being expressed in that organism at the time of extraction.

True

False

Expert Solution

1. The answer is False

RB gene is a tumor suppressor gene. The mutation in the RB gene causes retinoblastoma. The two copies of the mutated gene are required to exhibit the retinoblastoma phenotype. The individuals with genotype RB/Rb are carriers. They do not exhibit the phenotype. Retinal cells with genotype RB/rb will not exhibit the diseases. But have a high risk of causing cancer. The individuals with the genotype RB/rb transfers the mutated allele to their children.

2.

The correct option is C - controlled; uncontrolled

RB is a tumor suppressor gene. Tumor suppressor genes, in its normal state, check cell division. But when a mutation occurs on a tumor suppressor gene, it becomes inactivated and abnormal and results in uncontrolled cell division. Retinal cells with two copies of the normal RB gene (RB/RB) will show controlled growth. And retinal cells with two copies of the mutated gene (rb/rb) will show uncontrolled growth

Hence, the correct option - C

3.

The correct option is d - It will experience uncontrolled growth

Oncogenes are mutated proto-oncogenes Oncogenes promote uncontrolled and abnormal cell division and cause cancer. Oncogenic Ras promotes uncontrolled cell division. So a cell with oncogenic Ras will experience uncontrolled growth

hence, the correct option is d

4. The answer is False

New-gen sequencing is the new generation DNA sequencing that helps to determine a large number of the nucleotide sequence of the DNA at a time. After the extraction of DNA, the DNA has to be isolated and purified to apply the New-gen sequencing technology

gladiator answered 2 years ago

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