In: Biology
Which of the following events does NOT occur in fatty acid oxidation?
-use of NADPH as an energy source
-reduction of NAD+
-creation of ATP by ATP synthase
-hydrolysis of ATP to form AMP + PPi
Correct answer is use of NADPH as an energy source.
In Fatty acid oxidation NADPH is not used as an energy source.
NAD+ is reduced and form NADH+ H+.
During fatty acid oxidation FADH2 and NADH formed and one pair of electron is donated by each to electron transport chain (ETC). 1.5 and 2.5 ATP molecules are generated by FADH2 and NADH respectively. ATP synthase involves in this process.
Fatty acid activated to acyl-CoA and during activation, both phosphoanhydride bonds in ATP are hydrolysed to form AMP + PPi. Therefore, to activate a fatty acid molecule there is energy cost is equivalent to two ATP,