Why do there need to be SNARE proteins in both the membrane vesicle (the v-SNARE) and...

Why do there need to be SNARE proteins in both the membrane vesicle (the v-SNARE) and in the target membrane (the t-SNARE)? For example, why can’t there just be a single SNARE, only in the membrane vesicle?

Expert Solution

SNARE stands for SNAP REceptor.

v SNARE is present on vesicles and t SNARE is present on the membrane of target organelle.

Both of them are complementary in shape and size to each other. Both of them contain amino acids which can interact with each other and therefore help in the fusion of physical to the target membrane. These proteins are mainly involved in the transfer of molecules from vesicle to the target membrane mainly by the process of exocytosis.

This process involves the presence of SNARE on both the membranes, vesicle membrane and target organ oil membrane in order to be specific. If there were no SNARE on one of the membranes, then that membrane will fuse with any of the membrane by using other receptors. But to ensure that a given vesicle is using with its specific target organelle, these proteins must be present or both the membranes. Also if these proteins are present only on one of the membranes, then this membrane will not be able to recognise its target.

Therefore the overall function of the presence of SNARES on both the membranes is specificity, that is, to correctly transport the molecule present in vesicle to its target location.

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gladiator answered 1 year ago

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