Question

Discuss the consequences of the failure of a formed clot to dissolve.

Answer 1

Clots can also fail to dissolve after an injury has healed. This can lead to severe complications if not discovered and treated. The complications can be even life-threatening, especially if a clot forms in a blood vessel. The plaque and the clot can be responsible to obstruct the vessel and completely halt blood flow, leading to a heart attack or stroke. In addition, The clot (or a piece of it) breaks free and travels through the larger veins, through the vena cava, and through the right side of the heart, and then wedges into one of the pulmonary arteries or its branches, causing the pulmonary embolism (PE). This situation is also responsible to cause chronic thromboembolic pulmonary hypertension (CTEPH). The failure of blood clot to dissolve is also associated with several other conditions such as atherosclerosis, cancer, various infections, valvular heart disease and heart failure, autoimmune disorders, thrombocythemia, inflammatory bowel diseases.