If a piece of DNA has the sequence: ATGCCG, which of the following would indicate a...

If a piece of DNA has the sequence: ATGCCG, which of the following would indicate a frameshift insertion mutation?

ATGCCG

ATGGCG

TACGGC

ATGAACCG

Expert Solution

Q) answer: 4th option (ATGAACCG)

frameshift mutation:

we know that frameshift mutation is one type of genetic mutation. it is caused by the insertion or deletion of one or more nucleotides in DNA or mRNA. this mutation alters the reading frame and effects on protein function.

A frameshift mutation shifts the grouping of bases after this mutation the codon codes to different aminoacids and also affects protein function. these mutations are associated with different diseases like Crohn's disease, stay Sachs disease, etc.

a frameshift mutation is divided into two types they are: 1) frameshift insertion mutation 2) frameshift deletion mutation.

1) frameshift insertion mutation: nothing but the addition of one or more bases in a DNA or mRNA.

example: in ATGCCG sequences after insertion" A" ( alanine) converts to form ATGAACCG.

2) frameshift deletion mutation: it is caused by the removal of one or more bases in DNA or mRNA.

example: in ATGCCG sequence after deletion of "C" converts to form ATGCG.

gladiator answered 2 years ago

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