What are three main differences between High Performance Liquid Chromatography and Gas Chromatography?

Expert Solution

Differences between High performance liquid chromatography and Gas Chromatography:

1.The major difference between GC and HPLC lies in the phases used. While in GC, compounds of a mixture are seperated using a liquid (stationary) phase and a gas (mobile) phase, in case of HPLC the stationary phase is a solid while liquids make up mobile phase.

2. Another difference lies in temperature control during the process. In GC, there is an oven to contain the coloumn consinsting of gas phase and it can control the temperatures when the gases are passing through the column. On the other hand, there is not such provision of temperature control in HPLC.

3. The last difference pertains to the concentration of the compounds. In GC, it is the vapour pressure of the gases that decide the concentration of compounds whereas it is possible to increase or decrease the concentration of the compounds in HPLC.

queen_honey_blossom answered 1 year ago

High Performance Layer Chromatography Questions: 1. What are three main differences between High Performance Liquid Chromatography...

High Performance Layer Chromatography Questions: 1. What are three main differences between High Performance Liquid Chromatography and Gas Chromatography? 2. Which type of High Performance Liquid Chromatography is most widely used? Explain its characteristics. 3. What is the separation principle in Size Exclusion Chromatography? 4. Which is the most commonly used detector in High Performance Chromatography and why? 5. What is the difference between a bulk property detector and a specific property detector? 6. What is the difference between isocratic...

:ll The differences between Gradient elution in Liquid chromatography and Gradient elution in Gas chromatography??

what makes a sample ideal for high performance liquid chromatography?

1. Qualitative vs.Quantitative analysis for both High Performance Liquid Chromatography(HPLC) and High Performance Thin Layer Chromatography(HPTLC)

Explain how gas chromatography differs from liquid chromatography.

Compare the methods of capillary electrophoresis and high performance liquid chromatography. For each method, give an...

Compare the methods of capillary electrophoresis and high performance liquid chromatography. For each method, give an example of when it would be more advantageous than the other one.

Compare the methods of capillary electrophoresis and high performance liquid chromatography HPLC. For each method, give...

Compare the methods of capillary electrophoresis and high performance liquid chromatography HPLC. For each method, give an example of when it would be more advantageous than the other one.

1. Sketch diagrams of a gas chromatograph and a high performance liquid chromatograph. Label all the...

1. Sketch diagrams of a gas chromatograph and a high performance liquid chromatograph. Label all the parts and describe their use in one sentence each. Why is HPLC so important to modern industrial chemistry?

. What are the main characteristics of the mobile and stationary phases in gas chromatography? (10)...

. What are the main characteristics of the mobile and stationary phases in gas chromatography? (10) 2. What are the main applications and advantages of temperature programming in GC? What is the equivalent procedure in HPLC? (20) 3. What is the purpose of derivatization in HPLC? (10) 4. The following retention were measured in a column of 1.10 m: air : 18.0 s. methyl acetate: 1.98 min. methyl propionate: 2.24 min methyl n-butyrate: 7.93 min. The base width of the...

State which separation technique (Gas Chromatography, Liquid Chromatography, Electrophoresis, Size Exclusion Chromatography) would be the best...

State which separation technique (Gas Chromatography, Liquid Chromatography, Electrophoresis, Size Exclusion Chromatography) would be the best choice for each of the cases below and explain WHY? thank you! a. Separation of volatile components found in a perfume and that result in its characteristic fragrance. b. The determination of the molecular weight of a polymer that was synthesized by a friend in a polymer synthesis lab. Fall 2017 c. The separation of a nonvolatile pollutant found in drinking water. d. The...

Question