Section 2: The biological basis of the peanut allergy. In this section you should describe the...

Section 2: The biological basis of the peanut allergy.

In this section you should describe the biology of the peanut allergy . This should include:

What food(s) cause a reaction. Be sure to include a description of the biochemical components of the food(s) that cause a reaction.

This section should also examine the genetic and epigenetic basis of the peanut allergy
and include:

Is the peanut allergy passed on from generation to generation? How do you know?
What is the pattern of inheritance?
What is epigenetics and does epigenetic information affect or cause the peanut allergy ?

Finally, this section should include information about how the microbiota of your body affect the peanut allergy.

Expert Solution

Peanut is one of the most common food triggers of fatal anaphylaxis worldwide although peanut allergy affects only 1%‐2% of the general population. Peanuts are the source of highly potent allergenic proteins. It is emerging that the allergenicity of certain proteins is linked to their biological function.

Cookies, baked goods candies, ice cream, sauces that contain peanuts or nuts,

The tendency to develop allergies is often hereditary, which means it can be passed down through genes from parents to their kids. Researchers have pinpointed a region in the human genome associated with peanut allergy in U.S. children, offering strong evidence that genes can play a role in the development of food allergies. The team identified six genes — “LTB4R, PADI4, IL1R2, PPP1R3D, KLHL2, and ECHDC3” — as key drivers of the signalling networks that are active in a peanut allergy response.

Inheritance pattern not clear.

Epigenetics is the study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself. The levels of DNA methylation regulate whether people with genetic susceptibility to the peanut allergy actually developed it.

New research suggests allergy-causing antibodies live in the microbiome offering fresh insight into the role the got plays in the process.

gladiator answered 2 years ago

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