Low stem cell yield is a significant issue following cord stem
cell transplant for haematological conditions....
Low stem cell yield is a significant issue following cord stem
cell transplant for haematological conditions. Discuss the methods
that have been implemented and those that are currently under
investigation to improve outcome following cord stem cell
transplantation in relation to improvements in the CD34+ cell dose
provided.
The use of cord (umbilical) stem cells for adult haemopoietic
transplants is associated with a significant issue related to low
stem cell yield. Discuss the methods that have been implemented,
and those that are currently under investigation, to improve
outcome following cord stem cell transplantation in relation to
improvements in the CD34+ cell dose provided.
Discuss stem cell research, addressing the following
items:
List the sources of stem cells (at least four).
Explain which sources have been used successfully.
Describe the scientific research related to the use of stem
cells.
2. Define the following:
stem cell
pluripotent
embryonic stem cell
adult stem cell
3. Additionally, a new source of pluripotent stem cells was
reported in the fall of 2006. This source is not given in the list
above; if you are able to identify the...
Write about the following:
The major events that transform a hematopoietic stem cell into
a mature and naïve T cell
The microenvironment of the thymus where each stage of T-cell
development occurs.
The changes in expression of CD3, CD8 and TCR that occur during
T-cell development
The basis for positive and negative selection; relationship
between positive and negative selection and MHC restriction; and
negative selection and central tolerance.
General functions of Treg cells
Which of the following is considered a significant safety issue
for this laboratory?
The spectrophotometer measurements employ ultraviolet light,
which can damage eyes.
The solvents used in the lab are highly flammable, posing a fire
hazard.
Solutions are prepared in nitric acid, posing a risk for eye
injuries.
SCN- is highly toxic and must be handled with special care.
Calculate the voltage of the following cell at nonstandard
conditions:
Cu | Cu2+ (0.150 M) || Cu2+ (.0120 M) |
Cu
Convert your final answer to mV.
Group of answer choices
64.9 mV
-32.4 mV
-16.2 mV
32.4 mV
51. For a cell based on each of
the following reactions run at standard conditions, calculate the
emf of the cell, the standard free energy change of the reaction,
and the equilibrium constant of the reaction: Get the Potentials
from the table of standard reduction potentials available on
Blackboard)
a) Mn(s) + Cd
+2 (aq) ------> Mn+2 (aq) + Cd(s)
c) 2 Br
- (aq) + I2 (s) --------> Br2
(l) + 2 I - (aq)