Question

In: Nursing

You receive an order for 20% Dextrose solution, the pharmacy only stocks dextrose 50% vials. How...

You receive an order for 20% Dextrose solution, the pharmacy only stocks dextrose 50% vials. How would you instruct your technician to prepare this solution from Dextrose 50% and Sterile water for injection? You need to prepare one liter of solution.

Please provide illustration of how you calculated. Thanks.

Solutions

Expert Solution

Required concentration and volume of dextrose solution is 1 litre of 20% dextrose solution.
This is a w/v% as dextrose solutions are graded that way.

So, 20% w/v% is 20 grams dextrose in 100ml. For 1000 ml of same concentration, it is 200grams dextrose.

Available solution in pharmacy is 50%.
So 50% means 50 grams dextrose in 100ml of solution.

As total required dextrose is 200 grams, 200 grams will be present in 400ml of this solution.

The dextrose component is solved. Now volume of solution here is just 400ml. We need 600ml more to get required 1000ml.

So add 600ml of sterile water to this 400 ml of 50% dextrose solution.

The resultant solution will have 200 grams dextrose in 1000ml solution.
To confirm it's concentration, it will be (200/1000) x 100 = 20%, as required.


In short the instruction to the technicishould be "Take 400 ml of the available 50% dextrose solution and add 600ml of sterile water to it".

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