In: Nursing
The physician orders 500 mg of cefepime IV q.12h. The nurse has a
2 g vial of cefepime with the following instructions for
reconstitution:
Single-dose vials for IV/IM administration  | Amount of diluent to be added (mL)  | Approximate available volume (mL)  | Approximate  | 
1 g (IV)  | 10  | 11.3  | 100  | 
1 g (IM)  | 2.4  | 3.6  | 280  | 
2 g (IV)  | 10  | 12.5  | 160  | 
The nurse is correct to:
Ordered cefepime 500 mg IV q 12.h mean=s every 12 hours
nuRgse has given 2gm of vial of cefepime for reconstitution
Amount of diluent to be added is =10ml, approximate available volume=12.5 ml
Approximate available cefepime concentration =160mg/ml
means 160mg cefepime is in 1 ml
then 1mg will be in =1/160 ml
then 500mg will be available in =(1/160)X 500 ml
=3.1 ml