Question

For this discussion forum, find three interactions between medications and nutrients (food). List the interaction, foods to avoid while taking the medication, and describe key points that should be included in client education regarding the interactions.
You can use Epocrates to find your information https://online.epocrates.com/, or Medline Plus http://www.nlm.nih.gov/medlineplus/druginformation.html, or any other evidence based resource.

Please make an initial post by midweek, and respond to at least two other student's posts with substantial details that demonstrate an understanding of the concepts and critical thinking. Remember that your posts must exhibit appropriate writing mechanics including using proper language, cordiality, and proper grammar and punctuation. If you refer to any outside sources or reference materials, be sure to provide proper attribution and/or citation.

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Answer 1

List the interaction, foods to avoid while taking the medication, and describe key points that should be included in client education regarding the interactions.

You've likely heard the notices not to drink grapefruit juice with cholesterol drug. Notwithstanding, that isn't the main mix of sustenance and medications to stay away from. Grapefruit juice can communicate with various different meds, both remedy and over-the-counter. Also, numerous different nourishments generally associate with drugs, as well.

Steve Plogsted, BS, PharmD, BCNSP, CNSC, clinical drug specialist with Nutrition Support Service of Nationwide Children's Hospital in Columbus, Ohio, fills us in on five nourishments that most regularly communicate with pharmaceuticals.

Grapefruit Juice:

"Grapefruit juice can communicate with drugs in different ways," says Plogsted. One path is by expanding the ingestion of specific medications — similar to the case with a few, however not all, cholesterol-bringing down statins. MedinePlus prescribes staying away from grapefruit juice on the off chance that you are taking statins.

Grapefruit juice can likewise make the body use tranquilizes unusually, bringing about lower or higher than typical blood levels of the medication. Numerous solutions are influenced along these lines, including antihistamines, circulatory strain drugs, thyroid substitution drugs, conception prevention, stomach corrosive blocking drugs, and the hack suppressant dextromethorphan. It's best to keep away from or essentially lessen admission of grapefruit juice when taking these prescriptions.

Be that as it may, why is grapefruit juice of concern and not different citrus juices? As per Plogsted, grapefruit juice contains a class of mixes called furanocoumarins, which act in the body to modify the attributes of these medicines. Squeezed orange and different citrus juices don't contain these mixes. There is some worry for Seville oranges and the pummelo, which are relatives of the grapefruit.

Green Leafy Vegetables:

Blood-diminishing medications, for example, Coumadin® (warfarin) meddle with vitamin K-subordinate coagulating factors. Eating excessively green verdant vegetables, which are high in vitamin K, can diminish the capacity of blood-thinners to anticipate thickening. Be that as it may, you don't need to surrender greens by and large. Issues emerge from fundamentally and all of a sudden expanding or diminishing admission, as it can change the viability of the medication. So eat your greens in predictable sums.

Normal Black Licorice (Glycyrrhiza):

As indicated by Plogsted, glycyrrhiza — a characteristic fixing used to make dark licorice — can exhaust the assemblage of potassium while causing an expanded maintenance of sodium. At the point when the body is drained of potassium, the movement of digoxin, a pharmaceutical used to treat heart disappointment, can be extraordinarily improved, bringing about the heart not pulsating appropriately.

Glycyrrhiza can likewise diminish the adequacy of hypertension pharmaceuticals. What's more, individuals taking Coumadin® (warfarin) ought to be careful that glycyrrhiza can separate the medication, bringing about an expansion in the body's coagulating instrument.

Over the top measures of regular licorice ought to be stayed away from when taking these meds. Nonetheless, Plogsted takes note of that misleadingly enhanced dark licorice doesn't contain glycyrrhiza and isn't of concern.

Salt Substitutes:

Buyers taking digoxin for heart disappointment or ACE inhibitors for hypertension ought to be cautious with salt substitutes, which regularly supplant sodium with potassium. With an expanded utilization of potassium, the viability of digoxin can be diminished, bringing about heart disappointment. Also, those taking ACE inhibitors may see a noteworthy increment in blood potassium levels, as these medications are known to build potassium.

"There is no genuine need to maintain a strategic distance from salt substitutes, in spite of the fact that care ought to be taken when utilizing the item," say Plogsted. "On the off chance that the purchaser has diminished kidney work they ought to talk about the utilization of salt substitutes with their specialist."

Tyramine-Containing Foods:

High blood levels of the amino corrosive tyramine can cause an expansion in circulatory strain. A few solutions meddle with the breakdown of tyramine, including monoamine oxidase inhibitors (MAOIs) which treat despondency, and medications used to treat the indications of Parkinson's malady. Plogsted prompts those taking these medications to avoid tyramine-rich sustenances. The rundown is extensive and incorporates, yet isn't constrained to: chocolate, matured and develop cheeses, smoked and matured/aged meats, sausage, some prepared lunch meats, aged soy items and draft brews (canned and packaged lagers are OK).

While getting a solution for another pharmaceutical or taking another over-the-counter medication, Plogsted encourages purchasers to dependably read sedate cautioning names and ask their doctor as well as drug specialist about which nourishments or different medications they ought to keep away from or be worried about taking.

References:

1. Frankel EH. (2003). Basic Concepts. In: Hand book of food-drug Interactions, McCabe BJ, Frankel EH., Wolfe JJ (Eds.) pp. 2, CRC Press, Boca Raton, 2003.
2. Ayo JA, Agu H, Madaki I. Food and drug interactions: its side effects. Nutr Food Sci 2005;35(4):243-252 .10.1108/00346650510605630

Schmidt LE, Dalhoff K. Food-drug interactions. Drugs 2002;62(10):1481-1502 10.2165/00003495-200262100-00005