Question

Draw a transmembrane protein (as a cartoon) that functions in the Plasma Membrane. Draw the path for its production and deposition. The transmembrane protein must have 3 N- linked glycosylations and 2 O-linked glycosylations. For the N and O linked glycosylations the saccharide units should be cartoons – geometric shapes).Draw how the above transmembrane protein is bound by a receptor from another cell. The picture should include the structure of the terminal saccharide(s) that is /are contained on your transmembrane protein (above) and the few amino acid R groups of the receptor pocket which is binding the saccharides. Show how the amino acid R groups are interacting with (binding) the saccharides of the transmembrane protein.

Answer 1

step first: translation of protein on endoplasmic reticulum by the help of ribosomes and then transfer into the transmembrane section by diffusion process because of hydrophobic hydrophobic interactions.

second step: glycosylation of proteins or addition of carbohydrate molecules on a protein. glycosylation occurs at asn and ser residues.

Step third: Transfer of glycosylated protein into a vesicle. These vesicles used to the targate membrane and tratransport proteins.