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When veterinarians working in zoos treat animals with drugs they must take metabolic rate allometry into...

When veterinarians working in zoos treat animals with drugs they must take metabolic rate allometry into account in designing dosage regimes in order not to overdose larger animals. This is a practical application of the information we have about how body mass relates to the rates of cellular activities. What changes occur with respect to the abundance in mammalian cells of 'metabolic machinery' like mitochondria, key proteins, and key processes as we go from the cells of small species like mice to increasingly large species like cows or horses? What is the role of reversible phosphorylation in these differences?

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