Question

Explain what FSH does what would happen if exogenous FSH were given.

Give reasons why one would administer FSH.

Explain the importance of correct timing and mention the use of eCG (PMSG) as an alternative to FSH.

Explain importance of dose, mention superovulation, uterine capacity and use in MOET

Answer 1

When exogenous FSH is given it brings the bring out the development of multiple follicles till the dominant follicle is selected.This also causes rise in the levels of oestradiol and declines the concentrations of FSH

Administering of FSH is involved with the benefits of maturation of eggs to bring out ovulation.

Stimulation of follicles begin at the end of menstrual flow and thus FSH should be administered within3-6 days of menstrual period.

eCG also induces ovulation and growth of the follicles.They are usually taken with progesterone after the process of artificial insemination.

Importance of dose is considered because different individual are differently senstized to the levels of FSH and usually a standard dose of 150IU are employed.

Superovulation is the process more than one egg is induced to be released in a month and this is done by a controlled hyperstimulation process.Uterine capacity is the ability of the uterus to provide with the required nutrients to support placental growth.

In the process of MOET (Multiple Ovulation Embryo Transfer) in superior females are superovulated and inseminated and the embryos produced are introduced in a surrogate mother which depends on the uterine capacity.