Question

Compare and contrast oncogenes and tumor suppressors.

Answer 1

COMAPRISION AND CONTRASTING ONCOGENES & TUMOR SUPRESSOR GENES

ONCOGENES	TUMOR SUPRESSOR GENES
oncogenes result from the activation (turning on) of proto-oncogenes	tumor suppressor genes cause cancer when they are inactivated (turned off)
PROTO oncogenes are genes that normally promtes the cells to grow	Tumor suppressor genes are normal genes that slow down cell division, repair DNA mistakes, or guides the cells when to die called apoptosis
When a proto-oncogene mutates (changes) or there are large number of copies of it, it becomes a "dangerous" gene that can become permanently turned on.	When tumor suppressor genes don't work properly, cells can grow out of control, which can lead to cancer.
When this happens, the cell grows out of control, which can lead to cancer. This dangerous gene is called an oncogene.	tumor supressor genes normally keeps the cell from dividing too quickly. When something goes wrong with the gene, such as a mutation, cell division can get out of control.
A few cancer syndromes are caused by inherited mutations of proto-oncogenes that cause the oncogene to be turned on All cancer-causing mutations involving oncogenes are acquired, but not inherited	tumor suppressor genes have been found in some family cancer syndromes. They cause certain types of cancer to run in families. But most tumor suppressor gene mutations are acquired, but not inherited.
An oncogene could be compared with a gas pedal that is stuck down, which causes the cell to divide out of control.	Acquired mutations of this gene appear in a wide variety of cancers.
They generally activate oncogenes by: Chromosome rearrangements: Gene duplication	the abnormalities of the TP53 gene (which codes for the p53 protein) have been found in more than half of human cancers which is caused by tumor supressor gene.