Question

Question:

Is there a difference between oncogenes and tumor suppressor genes?

1. Yes, oncogenes are genes that can cause cancer when they become mutated to become proto-oncogenes, whereas tumor suppressor genes play no role in cancer.

2. Yes, oncogenes prevent cancer from forming unless they are mutated to become proto-oncogenes, whereas tumor suppressor genes stimulate the formation of cancer even in the absence of mutation.

3. No, oncogenes and tumor suppressor genes both stimulate the development of cancer, even in the absence of their becoming mutated.

4. Yes, oncogenes are mutated versions of genes that promote abnormal cell division (such as ras), whereas tumor suppressor genes are genes that normally hold cell division in check when it is not appropriate .

5. No, since both types of genes contribute to the development of cancer, there is no difference between them.

which is correct?

Answer 1

The correct answer is 4. Yes, oncogenes are mutated versions of genes that promote abnormal cell division (such as ras), whereas tumor suppressor genes are genes that normally hold cell division in check when it is not appropriate

Both oncogenes and tumor suppressor genes are genes that cause cancer. Oncogene in the non-mutated state is called a proto-oncogene. Proto-oncogenes after mutation become oncogenes that promote uncontrolled cell division that causes cancer. Tumor suppressor genes, in its normal state, check cell division. But after mutation, tumor suppressor gens becomes abnormal and inactivated and promotes uncontrolled cell division that causes cancer.

therefore the correct option is 4

oncogenes are mutated proto-oncogenes. Both oncogenes and tumor suppressor genes are genes causing cancer. So Option 1 is incorrect

Proto-oncogenes are oncogenes in the normal state. Both oncogenes and tumor suppressor gens causes cancer in the presence of a mutation. So option 2 is incorrect

Both oncogenes and tumor suppressor genes in the mutated state promote uncontrolled cell division and cause cancer. So option 3 is incorrect

Even though both oncogenes and tumor suppressor genes cause cancer, there are some differences between them. After mutation, activated proto-oncogenes promotes uncontrolled cell division. But tumor suppressor genes after mutation become inactivated and abnormal and promotes uncontrolled cell division. So option 5 is incorrect