what is celiac disease?

Expert Solution

ANSWER :

CELIAC DISEASE :

Celiac disease is an autoimmune disorder which runs in families.
Also called as non tropical sprue , celiac sprue or gluten sensitive enteropathy.

RIsk factors :

Family history of celiac disease
Autoimmune thyroid disorder
Type 1 diabetes mellitus
Addison's disease , downs syndrome

Etiology :

Gluten(protein present in barley , wheat and other grains) intake trigger's this disease.
Other triggering factors are , viral infections, emotional stress , pregnancy , childbirth etc
When people with celiac disease ingest gluten diet, their immune system reacts to that protein and damage the villi of small intestine.
Damaged villi cannot absorb sufficient vitamins , minerals and nutrients required for the body inspite of adequate intake of food.

Symptoms :

Anemia
Joint pains and fatigue
Bloating and nausea
Diarrhea, constipation
Mouth ulcers
Weight loss
Delayed puberty
Effects the growth of children
Failure to thrive in infants

DIagnosis :

Genetic testing to detect human leukocyte antigens
Serological tests to detect certain antibodies

Treatment :

Gluten free diet
Nutritional supplementation(gluten free) if malnourished

Complications :

Malnutrition
Small bowel cancer or intestinal lymphoma
Infertility and miscarriage
Peripheral neuropathy or seizures
Damage to bones and enamel of tooth

Nightingale answered 2 years ago

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