A drug that amplifies the effect of bradykinin would have what effect? What diseases could it...

A drug that amplifies the effect of bradykinin would have what effect? What diseases could it be prescribed to treat?

Solutions

Expert Solution

Ans.

Bradykinin is a potent nonapeptide which can induce inflammation.
Both, pharmacologically as well as physiologically, it belongs to peptides of the kinin proteins group.
It dilate arterioles by releasing prostacyclin, nitric oxide and endothelium derived hyperpolarizing factor and constrict veins by releasing prostaglandin F2.
It is an endothelium dependent potent vasodilator and mild diuretic in nature which may reduce blood pressure level.
In bronchus and gut, it causes non-vascular smooth muscles contraction, increases vascular permiability and also mediate pain.
Constriction and eventual blockade of many other fetal vessels, including the umbilical arteires and veins, is also mediated by bradykinin.
Angiotensin converting enzyme (ACE) inhibitors are a drug belonging to antihypertensive drugs class which increases level of bradykinin by preventing it's degradation thus amplifying it's blood pressure lowering effect.
ACE inhibitors are used for the treatment of hypertension and heart failure.
In patients treated with ACE inhibitors, it causes dry cough.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

What country could challenge the US for unipolarity and why, what would be the effect if...

What country could challenge the US for unipolarity and why, what would be the effect if that happened. Don't just answer yes or no, explain your answers fully.

Which of the following would be an example of an alteration in drug effect because of...

Which of the following would be an example of an alteration in drug effect because of a pharmacodynamic change? Question 5 options: a) diminished response to the heart rate lowering effects of a beta blocker in older adults because numbers of beta1 receptors on the heart decrease as the heart ages b) increased response to a sedative medication because of decreased metabolism in a patient with alcohol-induced liver disease c) increased toxicity from a chemotherautic drug in an older adult...

What effect would the magnification of the eyepiece have on resolution?

Name the drug and explain what effect it claims to have. Garcinia Cambogia, a tropical fruit...

Name the drug and explain what effect it claims to have. Garcinia Cambogia, a tropical fruit and a weight loss supplement Based on your knowledge of biological theories, is there anything about how this drug is supposed to work that makes you suspicious? Explain. Can you identify any credible science used in its claim? If so, in what way has the claim been exaggerated? can you help me understand more about Garcinia Gambogia ? Specifically, can you provide a better...

What are confounding variables, and what effect do they have on assessing cause-and-effect relationships? When would...

What are confounding variables, and what effect do they have on assessing cause-and-effect relationships? When would you prefer median to mean as a measure of central tendency? Why don’t we just sum the deviations from the mean to measure dispersion of a variable? When is it legitimate to use the empirical rule? How would you go about identifying outliers in your data?What would you do if you found an outlier?

what effect would each of the following have on the value of the firm? (a) A...

what effect would each of the following have on the value of the firm? (a) A new advertising campaign increases the sales of the firm substantially. (b) A new competitor enters the market. (c) The production department achieves a technological breakthrough that reduces production costs. (d) The firm is required to install pollution - control equipment. (e) The workforce votes to unionize. (f) The rate of interest rises. (g) The rate of inflation changes.

Question