In a simple synapse, neurotransmitter chemicals are released by Calcium induced exocytosis Ligand gated channels Graded...

In a simple synapse, neurotransmitter chemicals are released by

		Calcium induced exocytosis
		Ligand gated channels
		Graded potentials
		Saltatory conduction

Solutions

Expert Solution

(a) Calcium induced exocytosis

A synapse is a gap between Exxon terminal of first neuron (presynaptic neuron) and dendrites of second neuron(postsynaptic neuron).

Transmission at synapse occurs by following steps:

Action potentials arrive to the Exxon terminal of presynaptic neuron which result in opening of voltage gated calcium Ion channels on the membrane of presynaptic neuron.
Opening of calcium Ion channels result in influx of calcium ions which leads to calcium and dependent fusion of (neurotransmitter containing vesicles) synaptic vesicles with the membrane of presynaptic neuron.
Synaptic vesicles releases neurotransmitter by exocytosis.
Neurotransmitter diffusion occurs across the synaptic cleft and neurotransmitter to the remolecules binds to receptors which are present at postsynaptic neurons.
Binding of neurotransmitter to the receptors result in generation of postsynaptic potential.

Ligand gated Ion channels are opened when neurotransmitter binds to its receptors for the generation of postsynaptic potential and not for the release of neurotransmitter.

Graded potential are the alteration in membrane potential which are confined to a very small region of plasma membrane I.e. about 1-2 mm from their site of origin and do not play any role in neurotransmitter secretion.

Saltatory conduction is the mechanism of nerve impulse propagation in myelinated neurons. Due to uneven distribution of voltage gated Ion channels, as more number of voltage gated channels are present at nodes of ranvier as compared to the myelin sheath where they are almost absent.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Digitalis affects what protein? A) potassium ion channels b)ligand gated channels c)sodium/potassium ATPase d)calcium ATPase e)sodium...

Digitalis affects what protein? A) potassium ion channels b)ligand gated channels c)sodium/potassium ATPase d)calcium ATPase e)sodium ion channels

Explain how leak channels and gated channels differ. Discuss the role of calcium ions in the...

Explain how leak channels and gated channels differ. Discuss the role of calcium ions in the transmission of an action potential at the synapse. Define continuous propagation and saltatory propagation Identify and describe the three spinal meninges. Graded potentials produce an effect that increases with distance from the point of stimulation. produce an effect that spreads actively across the membrane surface without diminishing. always cause repolarization. may be either a hyperpolarization or a depolarization. are often all-or-none. please type it

A drug is designed to stimulate the voltage gated calcium channel at the neuronal synapse. What...

A drug is designed to stimulate the voltage gated calcium channel at the neuronal synapse. What effect on neuronal transmission would you expect to see and why?

Describe the structures involved in a typical chemical synapse (e.g., axon terminal [synaptic knob], voltage-gated calcium...

Describe the structures involved in a typical chemical synapse (e.g., axon terminal [synaptic knob], voltage-gated calcium channels, synaptic vesicles of presynaptic cell, synaptic cleft, neurotransmitter receptors of the postsynaptic cell).

Describe in detail chemical synapses, transmitter-gate (ligand-gated) channels and GPCRs. Diagrams and pictures can be included...

Describe in detail chemical synapses, transmitter-gate (ligand-gated) channels and GPCRs. Diagrams and pictures can be included but also text descriptions.

40. unlike membrane G protein couple receptors some ligand gated ion channels can be directly activated...

40. unlike membrane G protein couple receptors some ligand gated ion channels can be directly activated by cytosolic second messengers. a. true b. false 2. Arrestin-mediated internalization of GPCRs terminates the GPCR signaling. The binds of arrestin is facilitated by ____ . a. Inactivation of GPCR b. GPCR in endosome c. G-protein-couple receptor kinase (GRK)-mediated phosphorylation d. dephosphorylation of GPCR 12. Checkpoints halt the progress of the cell cycle when: a. The DNA cannot be repaired in cancer cells b....

If a pre-synaptic neuron released a neurotransmitter onto a post-synaptic neuron and caused potassium (K+) channels...

If a pre-synaptic neuron released a neurotransmitter onto a post-synaptic neuron and caused potassium (K+) channels to open, what effect would this have on the post-synaptic neuron? A. the post-synaptic neuron would likely generate an inhibitory post-synaptic potential (IPSP) B. the post-synaptic neuron would likely generate an excitatory post-synaptic potential C. the post-synaptic neuron would likely release a neurotransmitter D. the post-synaptic neuron would likely produce an action potential

Drag the labels onto the table to indicate which type(s) of gated ion channels are found in each membrane associated with a chemical synapse.

Drag the labels onto the table to indicate which type(s) of gated ion channels are found in each membrane associated with a chemical synapse. (The letters in the table refer to the lettered structures in the image above.) Labels can be used once, more than once, or not at all.

Subjects