Question

In: Biology

What are some of the specific functions of protein multimerization?

What are some of the specific functions of protein multimerization?

Solutions

Expert Solution

Multiprotein complex is known as a group of two or more associated polypeptide chains. Protein complexes are a form of quaternary structure. Proteins  are linked by non-covalent proteinprotein interactions in a multiprotein and different protein complexes show different degrees of stability over time.

Functions

Multimerization plays an important role in the function of proteins, can provide several functional advantages.

First-multimerization can be used as a means to control the function of proteins. Its includes activation or inactivation dependent on the multimeric state as well as enabling allosteric regulation and cooperativity between subunits.

Second-multimerization of proteins provides multivalency those increase the binding strength for substrates.

Third-multimerization create new active sites at interfaces between individual subunits.

Fourth-multimerization stabilize protein structures, especially in hyperthermophylic organisms.


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