In: Biology
What are some of the specific functions of protein multimerization?
Multiprotein complex is known as a group of two or more associated polypeptide chains. Protein complexes are a form of quaternary structure. Proteins are linked by non-covalent protein–protein interactions in a multiprotein and different protein complexes show different degrees of stability over time.
Functions
Multimerization plays an important role in the function of proteins, can provide several functional advantages.
First-multimerization can be used as a means to control the function of proteins. Its includes activation or inactivation dependent on the multimeric state as well as enabling allosteric regulation and cooperativity between subunits.
Second-multimerization of proteins provides multivalency those increase the binding strength for substrates.
Third-multimerization create new active sites at interfaces between individual subunits.
Fourth-multimerization stabilize protein structures, especially in hyperthermophylic organisms.