a) Why is the formation of α-ketoglutarate strongly regulated? b) Isocitrate dehydrogenase is inhibited by ATP...

a) Why is the formation of α-ketoglutarate strongly regulated?

b) Isocitrate dehydrogenase is inhibited by ATP and NADH and is activated by ADP. Assuming for a moment that not all of the allosteric effectors are known for this enzyme, propose one additional activator and one additional inhibitor. Justify the logic of your answer.

Expert Solution

gladiator answered 2 years ago

3. The rate of the citric acid cycle is controlled by— A) a-ketoglutarate dehydrogenase. B) isocitrate...

3. The rate of the citric acid cycle is controlled by— A) a-ketoglutarate dehydrogenase. B) isocitrate dehydrogenase. C) citrate synthase. D) all of the above. E) none of the above

hi, trying to understand the proccess of crebs cycle.. a. If Isocitrate dehydrogenase is inhibited by...

hi, trying to understand the proccess of crebs cycle.. a. If Isocitrate dehydrogenase is inhibited by axcess of citrate, and alpha ketogluterate by axcess of Suc-CoA, what exactly happeneds with the already made citrate and Suc-CoA? do they go back to being Acetyl coA and Alphaketogluterate respectively (and also become into fatty acids, amino acids and purins)? b. I also don't get how calcium signals for more production of Acethyl coA? who gets this signal? is that the Icam somthing...?...

Outline the mechanism of the conversion of α-ketoglutarate to succinyl-CoA catalyzed by α-ketoglutarate dehydrogenase complex. Put...

Outline the mechanism of the conversion of α-ketoglutarate to succinyl-CoA catalyzed by α-ketoglutarate dehydrogenase complex. Put these 5 steps in order: 1. decarboxylation 2. transacylation 3. dihydrolipoyl dehydrogenase activity 4. oxidation of 4-carbon group, reduction of lipoamide disulfide 5. enzymatical FADH2 reoxydation by NAD+

why is pyruvate dehydrogenase the regulated enzyme of pdc but not dihydrolipoyl transacetylase or dihydrolipoyl dehydrogenase?...

why is pyruvate dehydrogenase the regulated enzyme of pdc but not dihydrolipoyl transacetylase or dihydrolipoyl dehydrogenase? what causes defective regulation of pdc? if cells have energy, it will not run PDC instead what will it run?

1) Succinyl-CoA inhibits both citrate synthase and α-ketoglutarate dehydrogenase. How is succinyl-CoA able to inhibit both...

1) Succinyl-CoA inhibits both citrate synthase and α-ketoglutarate dehydrogenase. How is succinyl-CoA able to inhibit both enzymes?

Which subunit of ATP synthase is responsible for the catalysis of ATP formation? A. ? B....

Which subunit of ATP synthase is responsible for the catalysis of ATP formation? A. ? B. ? C. c D. a E. ?

a. Why Banks are regulated & supervised? (4 marks) b. What financial ratios best capture each...

a. Why Banks are regulated & supervised? b. What financial ratios best capture each aspects of the CAMELS Ratings? c. What is KYC? Why KYC is important in banking operations? (3mark) d. What are the impacts of money laundering on the economy? e. Would increased regulatory capital requirements lead to more consolidation among banks?(3marks) f. What are the consequences of bank failure g. Bank of Ghana requires Banks to maintain a statutory capital adequacy ratio (CAR) of 10%. Why strong...

Question