What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that...

What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that deficiency?

Expert Solution

The clinical deficiency presented by hemphilic people is a bleeding disorder that results in slow blood clotting process.In people with normal blood, there are presence of proteins known as clotting factors/coagulation factors specifically coagulation factor VIII and coagulation factor IX that function together together to to form a clot when bleeding occurs in our body.In case of hemophilic people, certain the mentioned clotting factor is missing or there is not enough of a certain clotting factor as a result of which clot is not formed when bleeding ocuurs.Hemophilia is of two types.The genetic cause is mutation in F8 gene that causes hemophilia A in which abnormal coagulation factor VIII or less of it is formed and mutation in F9 gene that causes hemophilia B in which abnormal coagulation factor VIII or less of it is formed.Severe hemophilia results when both the genes are mutated simultaneoulsy.

gladiator answered 2 years ago

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