In: Anatomy and Physiology
4. (4) make the perfect synapse using mixed parts –
a. What is it about your synapse which is special – is it fast? Has lots of control? Inexpensive....
"choose one characteristic "
b. choose a presynaptic neuron pick from: Norepi, Substance P, Glutamate or Acetylcholine – explain why you choose this one
c. choose a post synaptic response – NOT THE ONE WHICH THE NT IN PART B WOULD NORMALLY USE choose from M2, D2, NMDA, β2, GABA A explain why you choose this one
d. choose a post use processing model for the NT – IT SHOULD NOT MATCH YOUR OTHER CHOICES choose from 5HT, Glutamate, Dopamine, Acetylcholine
4. Synapse are the junctions between neuron's in the nervous system where transmitters are released. What is important about the synapse is that, they make sure the impulse travel in one direction only this is because the vessicles containing the neurotransmitter are only in the presynaptic membrane and the receptor molecules are only on the postsynaptic membrane, synapses also allow filtering out continual unnecessary or unimportant background stimuli, moreover synapse are very fast and precise.
b) presynaptic neurons is a neuron that fires the neurotransmitter as a result of an action potential entering the axon terminal.Acetylcholine is the most abudant neurotransmitter in the body, the most unique thing about acetylcholine is that it functions in the peripheral nervous system and the central nervous system both as an activator and inhibitor. In peripheral nervous system it causes skeletal muscles to contract and in central nervous system it inhibits the activation of cholinergic system.
c) Postsynaptic neuron in a neuron that receives the neurotransmitter after it has crossed synapse. GABA is a postsynaptic neuron which is unique in the sense that it is very fast and precise, their high speed is because they haave sensor which is used to measure the amount of calcium in the neuron.
d) Glutamate is the most abudant excitatory neurotransmitter in the vertebral nervous system, it serves as primary neurotransmitter for some localized brain region such as cerebellum granule cells and is involved in the cognitive function such as learning and memory in brain.