TRANSCRIPTION: What does RNA polymerase do in transcription? What is the end product of transcription?

Expert Solution

RNA polymerase = DNA dependent RNA polymerase.
It uses a DNA template to synthesize a complementary RNA.

The central dogma of life:
DNA ------> RNA -----> Protein
DNA ------> DNA: Replication: It is mediated by DNA polymerase
DNA ------> RNA: Transcription: It is mediated by RNA polymerase
RNA -----> Protein: Translation: It is mediated by the ribosome, tRNA, and amino acids.

In a human cell, DNA serves as the genetic material. It contains all the information for the proper growth and development of the cell. DNA codes for RNA which contains coding information to specify a protein sequence. A protein is the structural and functional component of a cell. All the cells in the body contain almost identical genome sequence (except for few immune system cells). However, all cells do not express all the genes all the time. Each tissue type expresses a specific set of genes at specific time period i.e. temporal and spatial expression. Such genes are known as tissue-specific genes. These tissue-specific genes are responsible for different structures and functions of different tissues in our body. The tissue-specific gene expression is mediated by epigenetic as well as transcriptional gene regulation.

Plus strand Sense strand Coding strand Non-template strand 5' 3' RNA 5' 3' 3' 5' Minus strand Anti-sense strand Non-coding strand Template strand

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Sydney Mullin answered 2 years ago

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