Answer each question with an explanation. 1) Assembly of myosin II into thick bipolar myosin II...

Answer each question with an explanation.

1) Assembly of myosin II into thick bipolar myosin II filaments in smooth muscle is known to be dependent on the Myosin II Light-Chain phosphorylation by Calmodulin dependent kinase (CamK, Myosin Light Chain Kinase is one of them). What second messenger would be/is responsible for Myosin II activation in smooth muscle?
a. cAMP
b. cGMP
c. Calcium
d. PIP3

2)Which of the following events does not occur during mitosis?
a. DNA condensation occurs
b. The nuclear envelope breaks down
c. Rb inactivation
d. APC mediated degradation of Cohesins

3)Which of the following statements is false?
a. Cyclins vary in concentration at different stages of the cell cycle
b. Cyclins help activate Cdks by phosphorylating them
c. Cyclins are degraded at specific times in the cell cycle.
d. Cyclins have no enzymatic activity on their own

4)Cells in G₀ phase could start cell cycle immediately upon receiving mitogens.
a. True
b. False

5)Microtubules capture chromosomes by its _________.
a. MTOC
b. plus end region
c. Microtubule Associating Proteins (MAPs)

Expert Solution

1) Assembly of myosin II into thick bipolar myosin II filaments in smooth muscle is known to be dependent on the Myosin II Light-Chain phosphorylation by Calmodulin dependent kinase (CamK, Myosin Light Chain Kinase is one of them). What second messenger would be/is responsible for Myosin II activation in smooth muscle?
d. PIP3 triggers the Sarcoplasmic Reticulum which in turn enables Ca2+ based complex

2)Which of the following events does not occur during mitosis?
c. Retinoblastoma protein inactivation triggers the start of mitosis.

3)Which of the following statements is false?
b. Cyclins help activate Cdks by phosphorylating them

4)Cells in G₀ phase could start cell cycle immediately upon receiving mitogens.
a. True, the dormant phase can be ended with mitogenic activation signalling fruitful conditiond for proliferation.

5)Microtubules capture chromosomes by its ...
c. Microtubule Associating Proteins (MAPs)

gladiator answered 2 years ago

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