1. What sorts of residues (i.e. what amino acid side chains)
would one expect to find on the surface of a protein with an
unusually high isoelectric point (e.g. 9.5). What if the pI were
unusually low (e.g. 3.4)?
2. When one talks about “protein-ligand” interactions, what
sorts of molecules can be “ligands?”
3. How would you explain the conformational selection model of
protein-ligand interactions to an educated lay person?