In: Nursing
Though Sickle cell anemia and Thalassemia are Genetic disorders, They differ in many ways.
SICKLE CELL ANEMIA | THALASSEMIA |
RBC becomes sickle shaped , an abnormal Hb is formed( Hbs). | Decreased production of polypeptides ( alpha and beta) that will leads to decreased Hb , hence it is devided into alpha thalassemia and beta thalassemia |
Commenly seen in African Americans | More commonly seen in mediterranean people |
Sickle cells adhere to the walls of blood vessels and causing hypoxia by obstructing the blood flow, results a medical emergency called Sickle cell crisis. | Mild Thalassemia usually requires no active treatment.But some Patients shows an iron overload in their blood that will results to damage of vital organs like Heart,Kidney etc |
Anemia mostly seen in homozygous patients, others are carriers. | Thalassemia major is a homozygous one , That requires active treatment( blood transfusion. |
persons will be resistant to malaria | Persons will be more prone to infections., Screening can be done for fetus to detect this abnormality |