In: Biology
Define Bioinformatics. What role does it play in healthcare IT? How does it help us in identifying what is the relationship between understanding the genetic basis of a disease and treating the disease? Discuss using example of Human Genome Project.
Bioinformatics is the specialized study in which completely one must understand how to biological information is processing through hereditary material and these hereditary materials are associated with cells, tissues, organelles, organs, entire living system.
Clinical bio-informatics in health care IT (information technology) is completely pertaining clinical and medical data of individual species or human beings regarding social system of medicines and implicating technologies compulsory to unravel human physiology associated mechanisms. The electronic recording of the genomic information associated with HIV, other pathogenic bacteria can be compared with "Human Genome project" finally useful to detect changes in the genome of humans due to viral infection followed by the genetic basis of a disease and treating the disease. These genome based-informatics are useful to develop novel therapeutic strategies based on structure & activity relationship of cell genome with infection
Thereby it is compulsory to know about the both disciplines remarkably. In the clinical aspects animal research associated bioinformatics can be used as models for human clinical informatics. For example, 75% of Drosophila genome and mice genome is nearly similar to human genome. In case of a few other aquatic animals such as Caenobacter elegans, other animal species, which can be, use to design models for bioinformatics to perform experiments & concurrently employed in human models to obtain clinical information based on ethical standards.
Microbial bio informatics, probiotics synthesis for human well being, genomics associated with proteomics for medicinal product study are the major areas on which these human normal microbioata have been studying by researchers. Majority of amino acid coded from sequences with conserved introns and these are profoundly homologous to consensus sequences of functional domains result in conserved peptides and proteins such as phosphatases, GTPases and membrane transporters etc. It has profoundly described these conserved sequences are originated from split between prokaryotes and eukaryotes by chance. In the bioinformatics E-value describes the conserved consensus sequence alignment has observed by chance with values lower than 10-3 with considerable significant for understanding the genetic basis of a disease and treating the microbial disease